malaria box Search Results


mmv malaria box mmv007571  (MolPort Inc)
90
MolPort Inc mmv malaria box mmv007571
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Mmv Malaria Box Mmv007571, supplied by MolPort Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mmv malaria box mmv007571/product/MolPort Inc
Average 90 stars, based on 1 article reviews
mmv malaria box mmv007571 - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
malaria box  (SCYNEXIS Inc)
90
SCYNEXIS Inc malaria box
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Malaria Box, supplied by SCYNEXIS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/malaria box/product/SCYNEXIS Inc
Average 90 stars, based on 1 article reviews
malaria box - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
malaria box  (Biomol GmbH)
90
Biomol GmbH malaria box
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Malaria Box, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/malaria box/product/Biomol GmbH
Average 90 stars, based on 1 article reviews
malaria box - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
malaria box hits  (Princeton BioMolecular Research Inc)
90
Princeton BioMolecular Research Inc malaria box hits
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Malaria Box Hits, supplied by Princeton BioMolecular Research Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/malaria box hits/product/Princeton BioMolecular Research Inc
Average 90 stars, based on 1 article reviews
malaria box hits - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
malaria box  (Evotec Inc)
90
Evotec Inc malaria box
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Malaria Box, supplied by Evotec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/malaria box/product/Evotec Inc
Average 90 stars, based on 1 article reviews
malaria box - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
novartis gnf malaria box dataset  (Novartis)
86
Novartis novartis gnf malaria box dataset
( A ) Inhibition of lysis by <t>MMV</t> <t>Malaria</t> Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).
Novartis Gnf Malaria Box Dataset, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/novartis gnf malaria box dataset/product/Novartis
Average 86 stars, based on 1 article reviews
novartis gnf malaria box dataset - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier

Image Search Results


( A ) Inhibition of lysis by MMV Malaria Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).

Journal: Scientific Reports

Article Title: Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

doi: 10.1038/srep37502

Figure Lengend Snippet: ( A ) Inhibition of lysis by MMV Malaria Box compounds was quantified by the activity of NLuc released following sorbitol lysis and was expressed as relative light units (RLU) relative to DMSO control. ( B ) Counter screen of top 20 NPP inhibitors from the MMV Malaria Box. Inhibition of NLuc was measured by adding the MMV compounds to parasites that had been lysed in water. Two compounds MMV665824 and MMV306025 strongly inhibited NLuc activity. Colours and numbers in ( A ) correspond to those in ( B ).

Article Snippet: Supplementary MMV Malaria Box compounds were obtained from MolPort (MMV007571 Molport catalog number is 007-936-716, MMV020439 Molport catalog number is 010-755-382).

Techniques: Inhibition, Lysis, Activity Assay, Control

( A ) EC 50 curves of sorbitol lysis of Nanoluciferase (NLuc) expressing parasites following treatment with serially diluted NPPB, furosemide and the MMV compounds. Sorbitol lysis was detected as an exponential growth rate in RLU over time (RLU/min −1 ) as a percentage between DMSO (100%) and PBS in place of sorbitol (0%). ( B ) Comparison of EC 50 of sorbitol-induced lysis measured by NLuc activity versus haemoglobin release of MMV007571 and MMV020439 treated iRBC. ( C ) Parasite proliferation after 72 h treatment with NPP inhibitors as measured by P. falciparum lactate dehydrogenase ( Pf LDH) assay. Pf LDH levels were measured at absorbance 620 nm as a percentage between DMSO (100%) and uninfected RBCs (0%) to determine EC 50 for parasite proliferation. In all graphs, values in parentheses indicate EC 50 for each drug.

Journal: Scientific Reports

Article Title: Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

doi: 10.1038/srep37502

Figure Lengend Snippet: ( A ) EC 50 curves of sorbitol lysis of Nanoluciferase (NLuc) expressing parasites following treatment with serially diluted NPPB, furosemide and the MMV compounds. Sorbitol lysis was detected as an exponential growth rate in RLU over time (RLU/min −1 ) as a percentage between DMSO (100%) and PBS in place of sorbitol (0%). ( B ) Comparison of EC 50 of sorbitol-induced lysis measured by NLuc activity versus haemoglobin release of MMV007571 and MMV020439 treated iRBC. ( C ) Parasite proliferation after 72 h treatment with NPP inhibitors as measured by P. falciparum lactate dehydrogenase ( Pf LDH) assay. Pf LDH levels were measured at absorbance 620 nm as a percentage between DMSO (100%) and uninfected RBCs (0%) to determine EC 50 for parasite proliferation. In all graphs, values in parentheses indicate EC 50 for each drug.

Article Snippet: Supplementary MMV Malaria Box compounds were obtained from MolPort (MMV007571 Molport catalog number is 007-936-716, MMV020439 Molport catalog number is 010-755-382).

Techniques: Lysis, Expressing, Comparison, Activity Assay, Lactate Dehydrogenase Assay